Cell Death in Development
نویسندگان
چکیده
منابع مشابه
Cell Death in Development
that the morphology of liver cells exposed to toxins, and Boston, Massachusetts 02115 lymphocytes treated with hormones, was the same as that described by the embryologist Glucksmann earlier Physiological mechanisms of cell death are used by in the century, they coined a new term, " apoptosis, " for multicellular organisms for development and morpho-cell deaths with this distinct morphology—whe...
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The mammalian immune system is a complex network of many cell types and proteins that collectively coordinate a protective response against foreign entities. The immune system can be divided into two broad categories: innate and adaptive immunity. Adaptive immunity, which is primarily mediated by T and B lymphocytes, first arose in jawed vertebrates and has several distinct features from the mo...
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Around the time of this journal’s first volume, the concept of PCD, i.e. the cell’s active participation in its own demise, was introduced using the example of a plant cell infected by a fungus (1). This was 7 decades before the flurry of apoptosis research in animals. Death during an incompatible interaction between a plant and a pathogen was proposed to function as a physical block to further...
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Cell death is a common and important feature of animal development, and cell death defects underlie many human disease states. The nematode Caenorhabditis elegans has proven fertile ground for uncovering molecular and cellular processes controlling programmed cell death. A core pathway consisting of the conserved proteins EGL-1/BH3-only, CED-9/BCL2, CED-4/APAF1, and CED-3/caspase promotes most ...
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condense, and the organelles and plasma membrane retain their integrity in a process Kerr and his colleagues and Martin C. Raff Developmental Neurobiology Programme named apoptosis. The dead cells or their fragments are rapidly phagocytosed by neighboring cells or macro-phages before there is any leakage of the contents of the cells, and thus they do not induce an inflammatory London, WC1E 6BT ...
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ژورنال
عنوان ژورنال: Cell
سال: 1999
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(00)80564-4